The average patients utilizes between approximately a gram to two grams a day. Dependency issues with cannabis are personality related and are not correlated to the potency of the cannabis used. Patients naturally select for potency.
Cannabis has biphasic properties, which means that low and high doses of the same substance can produce opposite effects. Small doses of cannabis tend to stimulate; large doses sedate. Too much THC, while not lethal, can amplify anxiety and mood disorders.
The following medications may enhance the effect of medicinal marijuana: Certain anti-depressants (e.g. fluoxetine, fluvoxamine, and nefazodone); Anti-acids (e.g. cimetidine and omeprazole); Antibiotics (e.g. clarithromycin and erythromycin)
Additionally Anti-fungals (e.g. itraconazole, fluconazole, ketoconazole, miconazole); Calcium channel blockers used for high blood pressure and heart disease (e.g. diltiazem, verapamil); HIV protease inhibitors (e.g. ritonavir, amiodarone, and isoniazid) also potentially decrease the effects of cannabis.
Rifampicin, Carbamazepine, Phenobarbital, Phenytoin, Primidone, Rifabutin, Troglitazone, Saint John's Wort...
Be aware Green Buddha is not a medical practioner and this information is merely meant as a guide. Please be sure to share with your physician that you are using medical cannabis and ask them specifically about any issues with other medications you are on.