Consistant medical studies have shown lower prevalence rates of obesity and diabetes mellitus in both recreational and medical cannabis users compared with people who have never used cannabis, suggesting a relationship between cannabinoids and peripheral metabolic processes. This study of more than 4,500 patients found that cannabis use was associated with lower levels of fasting insulin (less diabetes) and smaller waistlines.
Recreational and medical cannabis users have lower incident of diabetes, better insulin levels and smaller wastelines despite the fact their caloric intake is higher.
At the same time cannabis use is associated with an acute increase in caloric intake, and people who smoke/vape cannabis have higher average caloric intake levels than nonusers. Despite these associations with increased caloric intake, cannabis use has been associated with lower body mass
index (BMI) and a lower prevalence of obesity and diabetes mellitus. Why this is has not yet been determined.
Cannabis is also good for the neuropathic pain all too often associated with diabetes, by inhibiting glutamate release. Glutamate is one of the primary stimulatory neurotransmitters, but when present at excessive concentrations, it perpetuates neuropathic pain and may even provoke cell death after head injury or stroke. The endocannabinoids are naturally secreted after such insults and act to inhibit glutamate release, thereby alleviating neuropathic pain and reducing cell death.
Cannabinoids Can Halt Diabetes"It can be suggested that THCV may be useful for the treatment of the metabolic syndrome and/or type 2 diabetes (adult onset diabetes), either alone or in combination with existing treatments. Given the reported benefits of another non-THC cannabinoid, CBD in type 1 diabetes, a CBD/THCV combination may be beneficial for different types of diabetes mellitus.”